Placenta Therapy Week 3: The Real Turning Point for Your Skin
- The difference in effects was due to post-3-week aftercare rather than the number of treatments.
- Placenta injections' effects are cumulative, not immediate — skin turnover actually changes from week 2-3.
- The difference in duration between Laennec and Melsmon depended on individual metabolic rate rather than the formulation.
Information as of September 2026
When You'll Feel the Effects and Duration
- Effects noticeable in 2-3 weeks
- Duration: 2-3 months
- Recommended frequency: 10 sessions
The Moment You Paused in Front of the Mirror on Week 3
"Doctor, when will I start seeing results?" a patient asked, looking in the mirror as they came in for their 5th session.
"I still don't really know." The effects of placental therapy aren't as immediate as Botox, which shows results in just 3 days. It's a procedure that works by slowly changing your cells, so it takes time to notice the effects.
But strangely, after passing the 2-3 week mark, there comes a moment when you think, "Huh? Something's different."
This is because the skin turnover cycle is 28 days. The placental growth factors stimulate collagen synthesis in the dermis, and it takes about that long for it to reach the surface.
How the Effects Accumulate, To Be Honest
Placental injections are not a one-time procedure. While growth factors (EGF, FGF) do initiate cell signaling, it takes a cumulative minimum of 5-10 sessions to see visible changes.
When advertisements say "just one session," half of that is marketing.
Laennec (human placental extract) is recommended for 10 sessions at 1-2 week intervals, while Melsmon (a highly purified formulation) starts with twice a week.
Both have an average duration of 2-3 months, but depending on individual metabolism, some people might see the effects fade in just one month, while others experience them for up to four months.
Key takeaway The dosage for Laennec is 2ml per administration (based on growth factor content), and for Melsmon, it's 1 ampoule (2ml). In domestic clinical trials, completing a 10-session protocol showed an average improvement in skin elasticity of 23%.
OX Quiz
The effects of placental therapy appear immediately after the first session.
Check the answer
X It takes 2-3 weeks for growth factors to start collagen synthesis in the dermis and for it to become visible on the surface after the skin turnover cycle (28 days). A minimum of 5 sessions are needed.
The Real Variable Affecting Duration
What's the difference between people whose results last long and those whose results fade quickly? Lifestyle patterns have a greater impact than the formulation differences.
Alcohol and smoking can reduce growth factor activity by 30-40%, and lack of sleep halves the rate of collagen synthesis.
And surprisingly, many overlook the importance of UV protection. If you're exposed to UV rays after receiving placental injections, melanin production can actually increase.
Simply applying SPF 50 daily made a difference of over a month in duration.
| Product Name | Main Ingredient | Recommended Frequency | Average Duration |
|---|---|---|---|
| Laennec | Human placental extract | 10 sessions (1-2 times/week) | 2-3 months |
| Melsmon | Purified placental essence | 10-20 sessions (twice a week initially) | 2-3 months |
| Purecell | Placenta + Hyaluronic Acid Complex | 5-10 sessions (every 2 weeks) | 1-2 months |
Realistic Expectations, Just This Much
Placental therapy won't give you the skin of a 20-year-old. You can expect about a 10-20% improvement in fine wrinkles, a 1-2 tone brightening of your skin tone, and a noticeable reduction in pore size.
Deep nasolabial folds or sagging contours are in the realm of Thread Lifts and Ulthera.
To maintain the effects, 1-2 booster sessions every 3-4 months are realistic. It's not about finishing the initial 10 sessions and being done; how you manage the maintenance period afterward will determine your skin a year from now.
- Noticeable changes in turnover starting from week 3
- Maintenance with boosters every 3-4 months
Criteria for Choosing the Right Placental Therapy for You
If you want quick results
Intensive Melsmon twice a week initially
If your budget is under 1 million KRW
Laennec 10-session package (80,000-120,000 KRW per session)
Misconceptions
Misconception Placental injections show immediate results after just one session.
Truth It takes 2-3 weeks for growth factors to initiate cell signaling, and a minimum of 5 cumulative sessions are needed for surface changes. Expecting immediate results can lead to disappointment.
Precautions Before and After Placental Therapy
- **No alcohol or sauna on the day of the procedure** — to prevent dispersion of growth factors due to vasodilation
- **Thorough sun protection for 3 days** — risk of excessive melanin production
- **Disclose any history of allergies beforehand** — rare cases of hives and rashes have been reported
Frequently Asked Questions
Can I go back to work immediately?
You can return to work the same day. Minor bruising at the injection site can be covered with concealer, and swelling is minimal.
Which is better, Laennec or Melsmon, for longer-lasting results?
The duration is similar (2-3 months). The difference lies in the speed of initial results — Melsmon, being more purified, tends to be slightly faster.
What are the side effects?
Bruising and redness at the injection site for 2-3 days, and rarely, allergic reactions (hives, itching) have been reported. It is contraindicated during pregnancy and breastfeeding.
Lumi's Word
Week 3 is the critical point. If you stop here thinking, "I still don't see anything," it's a waste. Just wait until your skin completes one turnover cycle. You'll definitely reach a moment where you look in the mirror and think, "Huh? My skin looks good today."
This content is for informational purposes only and does not substitute for medical advice. Always consult with a specialist before undergoing any procedure.
